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Super User

Wednesday, 12 July 2017 11:54

Navicular Syndrome

Clinical Signs - Gait

  • Characteristic change in gait
  • Lameness aggravated when walking on hard ground or trotting in circles

Consult with your veterinarian if you suspect your horse may have Navicular syndrome as the clinical signs can vary.

Podcast:  Navicular Syndrome Update

From initial diagnosis to hoof care and bisphosphonate use, find out the newest information about this debilitating condition.

Recorded at Ask TheHorse Live


Healthy Bone Remodeling

Healthy bone remodeling happens in response to normal mechanical stress. Ideally, the cycle of bone remodeling is balanced. Resorption and formation work together to maintain healthy bones.

Bone remodeling in navicular syndrome happens in response to excessive mechanical stress. Resorption outpaces formation, leading to bone lesions.

Bone Remodeling
(roll over the image to see the effect of Navicular Syndrome)


Bone Resorption

  1. Osteoclasts, which are responsible for bone lysis, attach to the bone matrix
  2. H+ ions create an acidic microenvironment
  3. Lysosomal enzymes are released from the osteoclast
  4. The acidic environment:
    • exposes the organic matrix of the bone
    • activates the proteolytic enzymes
  5. Proteolytic enzymes destroy the organic matrix

Bone Formation

  1. Osteoblasts, which are responsible for bone formation, arrive at the resorption site
  2. Osteoblasts fill the cavity with new bone tissue
  3. Osteoblasts produce factors that aid in the mineralization of the bone tissue

health jointJoint Health and Degeneration

A healthy joint environment has a balance between destruction and repair (damage & growth).

Osteoarthritis is a vicious cycle, starting with excess stress on the joint that tips the balance within and leads to increasing levels of inflammation, damage, and pain.


Pathogenic Factors in Osteoarthritis

Biophysical Changes

  • Collagen network fracture
  • Unraveling of proteoglycan

Biochemical Changes

  • Proteolytic enzymes increased

At the molecular level, osteoarthritis is an imbalance between the molecules in the joint.

Peptides that promote the synthesis cartilage.

Friday, 07 July 2017 11:20

Sunshine Horses

Received the product today, thank you so much, we at sunshine horses truly appreciate your donation.

Kelly Holt,
Sunshine Horses, Inc.

Friday, 07 July 2017 11:19

Chattanooga State Community College

This opportunity [of practicing with the real product] provides our students with hands on training and provides an important service to the health of these magnificent animals.

Ann L. Cho, LVMT
Veterinary Technology Program, Chattanooga State Community College

Friday, 07 July 2017 11:18

Thoroughbred Retirement Foundation

Thank you so much for the generous Equimax donation and support of our horses!

Jessica Moore
Development Associate, Thoroughbred Retirement Foundatio

Friday, 07 July 2017 11:17

Sunkissed Acres Rescue and Retirement

Thank you so very, very much for your donation of Equimax.

CEO, Sunkissed Acres Rescue and Retirement

Friday, 07 July 2017 11:16

Kopper Top Life Learning Center

We appreciate your support and dedication to the horses. Thank you so much.

Deborah Meridith, LRT/CTRS
Riding Instructor, Kopper Top Life Learning Center

Friday, 07 July 2017 11:15

Horse Haven of Tennessee

Bimeda's generous donation of Equimax will help us get the abused and neglected horses is our care up to health. Thank you Bimeda!

Jenny Lindsey
Communications & Marketing Associate, Horse Haven of Tennessee

Friday, 07 July 2017 11:14

Heart of Phoenix Equine Rescue

We greatly appreciate the donation.

Tinia Creamer
Founder and Director, Heart of Phoenix Equine Rescue Inc.

Friday, 07 July 2017 10:52

Days End Farm Horse Rescue

The Equimax donation was a massive help and we cannot thank you enough!Your gift has made all the difference.

Erin Ochoa
Executive Director, Days End Farm Horse Rescue

Wednesday, 01 March 2017 15:46

Equine Product List

A list of Bimeda’s equine products

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Contact Us - US

Bimeda® US - Head Office
One Tower Lane, Suite 2250,
Oakbrook Terrace, IL 60181
Phone: 1 888 524 6332